Scientists have created a laser dermal regenerator from the "Star Trek"
Technology from a sci-fi universe of "Star Trek" continue to penetrate into our life. We have already read about the medical tricorder, we heard about the developments warp engine, evaluated dietary printers. Now it's time for "dermal regenerator" - a small device that can heal wounds and burns, and to restore the original structure of the epidermal tissue. Scientists from the University of Arizona under the direction of Kausalya Rege just engaged in the development of such a device.
The article published in the journal Advanced Functional Materials, researchers talk about the successful recovery of the damaged tissues of the skin of animals by means of silk and gold nanoparticles using laser beams. As part of the experimental verification technology has quickly heal damaged soft tissues of pig intestines, as well as the damaged section of mouse skin. Researchers note that in the case of pig intestines scar created, which unites two portions of the damaged tissue was almost seven times more durable than in the conventional method of suturing wounds.
Scientists note that the use of conventional recovery methods, such as sutures, medical adhesive and staples often the wounds can be opened again, slowing down the process of tissue repair. Their own development promises to eliminate this problem.
"We are trying to develop a method for more rapid bonding of damaged tissues and more rapid recovery," - said Dipandzhan Ghosh, co-author of the study.
From left to right: comparison condition of the wound after use of conventional seam adhesive and medical laser to 0 and day 2 after the injury
When using the "healing" of the laser beam must be focused at the wound site. In fact, the beam does not heal, it only triggers a reaction that leads to rapid healing of wounds. As the bonding material scientists use gold nanotubes are placed in the matrix protein of silk taken from silkworm cocoons. Positioned on the skin protein called fibroin forms a bond with collagen - the protein, forming the basis of the connective tissue between the skin cells. When exposed to near-infrared radiation on the golden nanotubes, they generate heat, which causes the silk protein to create new cell connections, thus forming a strong bond between the damaged areas.
Usable laser length near infrared range of about 800 nanometers. This is sufficient for the heating of gold nanoparticles, but it does not cause any damage to the skin.
Developers have created two kinds of healing "sealant", one for wet environments, not biodegradable under the influence of water, the other - for dry environment, which irritate exposed to water. First, scientists have tested the healing of porcine intestinal tissue. After applying the healing material, researchers noted that tissue strength at the site of healing was seven times more durable than conventional sutures and medical adhesive. According to Ghosh, tissue repair functions completely normally like and intact. Scientists then tested the healing agent for dry environment, causing it on the skin of laboratory rodents. Causing the paste on the cut and the wound checked in 2 days, scientists have noted a significantly higher efficiency of healing compared with braces and medical glue. In addition, the process of application and the launch took quite a bit of time - about four minutes.
Since the near-infrared light can penetrate deep into the tissue, Ghosh and his colleagues hope to in the future use of the technology developed for the recovery of blood vessels and nerve channels - fabrics, usually located deep under the skin, the recovery of which takes much more time compared to normal tissue.
"Staple nerves and blood vessels usually is a much more difficult task for even the most skilled surgeons," - says Ghosh.
The scientists believe that the value of silk and gold material is not excessively high and the underlying costs of health centers in this case will fall to the laser equipment.
Currently, scientists are watching how the laser-activated sealant Medical behaves in the body of live rats. If the tests are successful, the scientists are going to go to the pigs, and then finally to the men.
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